Anticorps Monoclonal anti-CD11c

CD11c Monoclonal Antibody for FC

Hôte / Isotype

Armenian Hamster / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Atlantic Blue™ Fluorescent Dye

CloneNo.

N418

N° de cat : AB-65130

Synonymes

AI449405, Cd11c, Cr4, integrin alpha X, Itgax



Applications testées

Résultats positifs en cytométriesplénocytes de souris,

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

AB-65130 cible CD11c dans les applications de FC et montre une réactivité avec des échantillons souris

Réactivité souris
Hôte / Isotype Armenian Hamster / IgG
Clonalité Monoclonal
Type Anticorps
Immunogène Cellules dendritiques de rate de souris
Nom complet integrin alpha X
Numéro d’acquisition GenBankBC167225
Symbole du gène Itgax
Identification du gène (NCBI) 16411
Conjugaison Atlantic Blue™ Fluorescent Dye
Excitation/Emission maxima wavelengths404 nm / 458 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).

Protocole

Product Specific Protocols
FC protocol for Atlantic Blue™ CD11c antibody AB-65130Download protocol
Standard Protocols
Click here to view our Standard Protocols