Anticorps Monoclonal anti-CD11c

CD11c Monoclonal Antibody for FC

Hôte / Isotype

Armenian Hamster / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

PE Fluorescent Dye

Publications(5)

CloneNo.

N418

N° de cat : PE-65130

Synonymes

AI449405, Cd11c, Cr4, integrin alpha X, Itgax, N418



Applications testées

Résultats positifs en cytométriesplénocytes de souris,

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

FCSee 5 publications below

Informations sur le produit

PE-65130 cible CD11c dans les applications de FC et montre une réactivité avec des échantillons souris

Réactivité souris
Réactivité citéesouris
Hôte / Isotype Armenian Hamster / IgG
Clonalité Monoclonal
Type Anticorps
Immunogène Cellules dendritiques de rate de souris
Nom complet integrin alpha X
Numéro d’acquisition GenBankBC167225
Symbole du gène CD11c
Identification du gène (NCBI) 16411
Conjugaison PE Fluorescent Dye
Excitation/Emission maxima wavelengths496 nm, 565 nm / 578 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide and 0.5% BSA
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).

Protocole

Product Specific Protocols
FC protocol for PE CD11c antibody PE-65130Download protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseFC

Nutrients

The Potential Role of Moringa oleifera Lam. Leaf Proteins in Moringa Allergy by Functionally Activating Murine Bone Marrow-Derived Dendritic Cells and Inducing Their Differentiation toward a Th2-Polarizing Phenotype

Authors - Chuyu Xi
mouseFC

Adv Healthc Mater

Pathogen-mimicking Nanoparticles Based on Rigid Nanomaterials as an Efficient Subunit Vaccine Delivery System for Intranasal Iimmunization

Authors - Hongping Wan
mouseFC

Int J Biol Macromol

Mucoadhesive chitosan-catechol as an efficient vaccine delivery system for intranasal immunization

Authors - Kai Deng
mouseFC

Int J Pharm

A manganese-oxide nano-rambutan as the intrinsic modifier for hypericin delivery and triple-negative breast cancer treatment

Authors - Weixin Zhou
mouseFC

Mater Today Bio

Self-assembly of paclitaxel derivative and fructose as a potent inducer of immunogenic cell death to enhance cancer immunotherapy

Authors - Manzhen Li
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