Anticorps Monoclonal anti-CD11c
CD11c Monoclonal Antibody for FC
Hôte / Isotype
Armenian Hamster / IgG
Réactivité testée
souris
Applications
FC
Conjugaison
PE Fluorescent Dye
CloneNo.
N418
N° de cat : PE-65130
Synonymes
Galerie de données de validation
Applications testées
| Résultats positifs en cytométrie | splénocytes de souris, |
Dilution recommandée
| Application | Dilution |
|---|---|
| This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results. | |
| Sample-dependent, check data in validation data gallery | |
Applications publiées
| FC | See 5 publications below |
Informations sur le produit
PE-65130 cible CD11c dans les applications de FC et montre une réactivité avec des échantillons souris
| Réactivité | souris |
| Réactivité citée | souris |
| Hôte / Isotype | Armenian Hamster / IgG |
| Clonalité | Monoclonal |
| Type | Anticorps |
| Immunogène | Cellules dendritiques de rate de souris |
| Nom complet | integrin alpha X |
| Numéro d’acquisition GenBank | BC167225 |
| Symbole du gène | CD11c |
| Identification du gène (NCBI) | 16411 |
| Conjugaison | PE Fluorescent Dye |
| Excitation/Emission maxima wavelengths | 496 nm, 565 nm / 578 nm |
| Forme | Liquide |
| Méthode de purification | Purification par affinité |
| Tampon de stockage | PBS with 0.09% sodium azide and 0.5% BSA |
| Conditions de stockage | Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment. |
Informations générales
Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits (PMID: 9779984). CD11c, also known as integrin αX, is a type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, a subset of B cells, NK cells and dendritic cells (PMID: 2897326; 1680915; 1694698; 17389580). As a result of its high level of expression on most dendritic cells, CD11c is typically considered to be a marker of conventional dendritic cells (PMID: 27119555). CD11c forms an α/β heterodimer with CD18 (integrin β2). CD11c/CD18 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis (PMID: 1671533).
Protocole
| Product Specific Protocols | |
|---|---|
| FC protocol for PE CD11c antibody PE-65130 | Download protocol |
| Standard Protocols | |
|---|---|
| Click here to view our Standard Protocols |
Publications
| Species | Application | Title |
|---|---|---|
Nutrients The Potential Role of Moringa oleifera Lam. Leaf Proteins in Moringa Allergy by Functionally Activating Murine Bone Marrow-Derived Dendritic Cells and Inducing Their Differentiation toward a Th2-Polarizing Phenotype | ||
Adv Healthc Mater Pathogen-mimicking Nanoparticles Based on Rigid Nanomaterials as an Efficient Subunit Vaccine Delivery System for Intranasal Iimmunization | ||
Int J Biol Macromol Mucoadhesive chitosan-catechol as an efficient vaccine delivery system for intranasal immunization | ||
Int J Pharm A manganese-oxide nano-rambutan as the intrinsic modifier for hypericin delivery and triple-negative breast cancer treatment | ||
Mater Today Bio Self-assembly of paclitaxel derivative and fructose as a potent inducer of immunogenic cell death to enhance cancer immunotherapy |
