Anticorps Monoclonal anti-CD11c

CD11c Monoclonal Antibody for IF-P

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain et plus (1)

Applications

IF-P

Conjugaison

CoraLite®594 Fluorescent Dye

Publications(2)

CloneNo.

2F1C10

N° de cat : CL594-60258

Synonymes

2F1C10, CD11 antigen-like family member C, Integrin alpha X, Integrin alpha-X, ITGAX

---

Galerie de données de validation

• 

  IF Staining of human tonsillitis using CL594-60258

  Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 CD11c/Integrin Alpha X antibody (CL594-60258, Clone: 2F1C10 ) at dilution of 1:200.

• 

  IF Staining of human tonsillitis using CL594-60258

  Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 CD11c/Integrin Alpha X antibody (CL594-60258, Clone: 2F1C10 ) at dilution of 1:200.

• 

  IF Staining of human tonsillitis using CL594-60258

  Immunofluorescent analysis of (4% PFA) fixed human tonsillitis tissue using CoraLite®594 CD11c/Integrin Alpha X antibody (CL594-60258, Clone: 2F1C10 ) at dilution of 1:200, CoraLite®488 CD8 antibody (CL488-66868, Clone: 1G2B10, green).

---

Applications testées

• Résultats positifs en IF-P: tissu d'amygdalite humain,

Dilution recommandée

• Immunofluorescence (IF)-P: IF-P : 1:50-1:500

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Applications publiées

• IF: See 2 publications below

Informations sur le produit

CL594-60258 cible CD11c dans les applications de IF-P et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: souris
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CD11c Protéine recombinante Ag11350
• Nom complet: integrin, alpha X (complement component 3 receptor 4 subunit)
• Masse moléculaire calculée: 1169 aa, 129 kDa
• Numéro d’acquisition GenBank: BC038237
• Symbole du gène: CD11c
• Identification du gène (NCBI): 3687
• Conjugaison: CoraLite®594 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 588 nm / 604 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 50% glycerol, 0.05% Proclin300, 0.5% BSA
• Conditions de stockage: Stocker à -20 °C. Éviter toute exposition à la lumière. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

Integrins are cell adhesion receptors that are heterodimers composed of non-covalently associated α and β subunits. CD11c/Integrin alpha X is a 145-150 kDa type I transmembrane glycoprotein present on a variety of cells, including monocytes/macrophages, granulocytes, NK cells and dendritic cells. Integrin alpha X/beta 2 acts a receptor for fibrinogen and is important in monocyte adhesion and chemotaxis. And this anitbody is CL594(Ex/Em 593 nm/614 nm) conjugated.

Publications

Species	Application	Title
mouse	IF	JCI Insight; Acquired Immunostimulatory Phenotype of Migratory CD103+ Dendritic Cells Promotes Alloimmunity Following Corneal Transplantation; Authors - Tomas Blanco
mouse	IF	Mucosal Immunol; Conventional type I migratory CD103+ dendritic cells are required for corneal allograft survival; Authors - Tomas Blanco

{{ptg:RelatedPrimaryAntibodies}}