Anticorps Recombinant de lapin anti-CD122/IL-2RB

CD122/IL-2RB Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241677C9

N° de cat : 84389-2-PBS

Synonymes

IL2RB, IL 2RB, IL 2R subunit beta, IL 2 receptor subunit beta, High affinity IL-2 receptor subunit beta

---

Galerie de données de validation

• 

  WB analysis using 84389-2-RR (same clone as 84389-2-PBS)

  NK-92 cells were subjected to SDS PAGE followed by western blot with 84389-2-RR (CD122/IL-2RB antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84389-2-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 84389-2-RR

  Biolayer interferometry (BLl) kinetic assays of 84389-2-RR against Human CD122/IL-2RB were performed. The affinity constant is 32.2 nM.

---

Informations sur le produit

84389-2-PBS cible CD122/IL-2RB dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: interleukin 2 receptor, beta
• Masse moléculaire calculée: 551 aa, 61 kDa
• Poids moléculaire observé: 70 kDa
• Numéro d’acquisition GenBank: BC025691
• Symbole du gène: IL2RB
• Identification du gène (NCBI): 3560
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. The beta subunit (IL2RB, also known as CD122 and p75) is involved in receptor mediated endocytosis and transduces the mitogenic signals of nterleukin 2.

{{ptg:RelatedPrimaryAntibodies}}