Anticorps Recombinant de lapin anti-CD122/IL-2RB

CD122/IL-2RB Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

PE Fluorescent Dye

CloneNo.

241677H7

N° de cat : PE-FcA98151

Synonymes

IL2RB, CD122, High affinity IL-2 receptor subunit beta, IL 2 receptor subunit beta, IL 2R subunit beta

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Galerie de données de validation

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  FC experiment of human PBMCs using PE-FcA98151

  1x10^6 human PBMCs were surface stained with APC Anti-Human NCAM1/CD56, and 5 ul PE Anti-Human CD122/IL-2RB Rabbit RecAb (PE-FcA98151, Clone:241677H7) or PE Rabbit IgG Isotype Control RecAb (PE-FcA98136, Clone: 240953C9). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

PE-FcA98151 cible CD122/IL-2RB dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: interleukin 2 receptor, beta
• Masse moléculaire calculée: 551 aa, 61 kDa
• Numéro d’acquisition GenBank: BC025691
• Symbole du gène: IL2RB
• Identification du gène (NCBI): 3560
• Conjugaison: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to the ability to bind interleukin 2. The low-affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. The beta subunit (IL2RB, also known as CD122 and p75) is involved in receptor-mediated endocytosis and transduces the mitogenic signals of interleukin 2.

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