Anticorps Monoclonal anti-CD122/IL-2RB

CD122/IL-2RB Monoclonal Antibody for WB, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

3A12C7

N° de cat : 60174-1-PBS

Synonymes

IL2RB, 3A12C7, CD122, High affinity IL-2 receptor subunit beta, IL 2 receptor subunit beta

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Galerie de données de validation

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  WB analysis using 60174-1-Ig (same clone as 60174-1-PBS)

  Untreated and PNGase F-treated lysates of NK-92 cells were subjected to SDS PAGE followed by western blot with 60174-1-Ig (CD122/IL2RB antibody) at dilution of 1:10000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60174-1-PBS in a different storage buffer formulation.

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  WB analysis of Recombinant protein using 60174-1-Ig (same clone as 60174-1-PBS)

  Recombinant protein were subjected to SDS PAGE followed by western blot with 60174-1-Ig (IL2RB antibody) at dilution of 1:600 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60174-1-PBS in a different storage buffer formulation.

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  Cytometric bead array standard curve of MP50451-1

  Cytometric bead array standard curve of MP50451-1, CD122/IL2RB Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60174-3-PBS. Detection antibody: 60174-1-PBS. Standard:Ag3929. Range: 0.098-25 ng/mL.

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  Cytometric bead array standard curve of MP50451-2

  Cytometric bead array standard curve of MP50451-2, CD122/IL2RB Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60174-2-PBS. Detection antibody: 60174-1-PBS. Standard:Ag3929. Range: 0.098-50 ng/mL.

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Informations sur le produit

60174-1-PBS cible CD122/IL-2RB dans les applications de WB, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CD122/IL-2RB Protéine recombinante Ag3929
• Nom complet: interleukin 2 receptor, beta
• Masse moléculaire calculée: 551 aa, 61 kDa
• Poids moléculaire observé: 75 kDa, 61 kDa
• Numéro d’acquisition GenBank: BC025691
• Symbole du gène: IL2RB
• Identification du gène (NCBI): 3560
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

The interleukin 2 receptor, which is involved in T cell-mediated immune responses, is present in 3 forms with respect to ability to bind interleukin 2. The low affinity form is a monomer of the alpha subunit and is not involved in signal transduction. The intermediate affinity form consists of an alpha/beta subunit heterodimer, while the high affinity form consists of an alpha/beta/gamma subunit heterotrimer. The beta subunit (IL2RB, also known as CD122 and p75) is involved in receptor mediated endocytosis and transduces the mitogenic signals of nterleukin 2.

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