Anticorps Monoclonal anti-IL-7Ra/CD127

IL-7Ra/CD127 Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2a, kappa

Réactivité testée

souris

Applications

FC

Conjugaison

PE Fluorescent Dye

Publications(1)

CloneNo.

A7R34

N° de cat : PE-65093

Synonymes

CD127, Il7r, A7R34, IL 7Ralpha, IL- 7Ralpha



Applications testées

Résultats positifs en cytométriesplénocytes de souris,

Dilution recommandée

ApplicationDilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

FCSee 1 publications below

Informations sur le produit

PE-65093 cible IL-7Ra/CD127 dans les applications de FC et montre une réactivité avec des échantillons souris

Réactivité souris
Réactivité citéesouris
Hôte / Isotype Rat / IgG2a, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Protéine de fusion IL-7Ra-IgG1
Nom complet interleukin 7 receptor
Numéro d’acquisition GenBankBC089571
Symbole du gène CD127
Identification du gène (NCBI) 16197
Conjugaison PE Fluorescent Dye
Excitation/Emission maxima wavelengths496 nm, 565 nm / 578 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide and 0.1% gelatin
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD127, also known as IL-7R subunit alpha (IL-7Rα), is a type I membrane glycoprotein expressed on thymocytes, B cell precursors, most T cells, and some lymphoid and myeloid cells (PMID: 8415665). IL-7R is a heterodimer composed of CD127 and IL-2Rγ (CD132), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15 (PMID: 8266077; 9862091). IL-7R plays critical roles in lymphocyte development and homeostasis (PMID: 26336149). CD127 can also act as a receptor for thymic stromal lymphopoietin (TSLP) (PMID: 10974032).

Protocole

Product Specific Protocols
FC protocol for PE IL-7Ra/CD127 antibody PE-65093Download protocol
Standard Protocols
Click here to view our Standard Protocols

Publications

SpeciesApplicationTitle
mouseFC

J Inflamm Res

Sodium Butyrate Ameliorates Type 2 Diabetes-Related Sarcopenia Through IL-33-Independent ILC2s/IL-13/STAT3 Signaling Pathway

Authors - Yuan Cao
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