Anticorps Polyclonal de lapin anti-CD134/OX40

CD134/OX40 Polyclonal Antibody for WB, FC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, FC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 20006-1-PBS

Synonymes

TNFRSF4, ACT35, ACT35 antigen, CD134, OX40

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Galerie de données de validation

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  WB analysis using 20006-1-AP (same clone as 20006-1-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 20006-1-AP (CD134/OX40 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 20006-1-PBS in a different storage buffer formulation.

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  FC experiment of human PBMCs using 20006-1-AP (same clone as 20006-1-PBS)

  1X10^6 day 3 PHA treated human PBMCs were surface stained with 0.2 ug Anti-Human CD134/OX40 (20006-1-AP) and CoraLite®750-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) at dilution 1:1000 (red), or unstained (blue). Unstimulated human PBMCs were surface stained with 0.2ug Anti-Human CD134/OX40 (20006-1-AP) and CoraLite®750-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L) at dilution 1:1000 (black dashed). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 20006-1-PBS in a different storage buffer formulation.

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Informations sur le produit

20006-1-PBS cible CD134/OX40 dans les applications de WB, FC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Peptide
• Nom complet: tumor necrosis factor receptor superfamily, member 4
• Masse moléculaire calculée: 29 kDa
• Poids moléculaire observé: 50-55 kDa, 40 kDa
• Numéro d’acquisition GenBank: NM_003327
• Symbole du gène: CD134
• Identification du gène (NCBI): 7293
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD134 (OX40) is a member of the TNFR-superfamily of receptors. Predominantly expressed on activated T cells, CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule. CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmunity (PMID: 26215166). CD134 can interact with TRAF2, TRAF3, and TRAF5.

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