Anticorps Recombinant de lapin anti-CD134/OX40

CD134/OX40 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241398B4

N° de cat : 84247-4-PBS

Synonymes

TNFRSF4, OX40L receptor, OX40, CD134, ACT35 antigen

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Galerie de données de validation

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  WB analysis using 84247-4-RR (same clone as 84247-4-PBS)

  Various lysates were subjected to SDS PAGE followed by western blot with 84247-4-RR (OX40/TNFRSF4 antibody) at dilution of 1:4000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84247-4-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84247-4-RR

  Biolayer interferometry (BLl) kinetic assays of 84247-4-RR against Human CD134/OX40 were performed. The affinity constant is 5.21 nM.

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Informations sur le produit

84247-4-PBS cible CD134/OX40 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: tumor necrosis factor receptor superfamily, member 4
• Masse moléculaire calculée: 29 kDa
• Poids moléculaire observé: 45-50 kDa
• Numéro d’acquisition GenBank: NM_003327
• Symbole du gène: CD134
• Identification du gène (NCBI): 7293
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD134 (OX40) is a member of the TNFR-superfamily of receptors. Predominantly expressed on activated T cells, CD134 is activated by its cognate ligand CD134L (OX40L) and functions as a T cell co-stimulatory molecule. CD134-CD134L interactions have been proposed as a potential therapeutic target for treating autoimmunity (PMID: 26215166). CD134 can interact with TRAF2, TRAF3, and TRAF5.

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