Anticorps Monoclonal anti-CD138/Syndecan-1

CD138/Syndecan-1 Monoclonal Antibody for WB, Sandwich ELISA, Indirect ELISA, Sample test

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Sandwich ELISA, Indirect ELISA, Sample test

Conjugaison

Non conjugué

CloneNo.

1B6A2

N° de cat : 60185-1-PBS

Synonymes

CD138, 1B6A2, SDC, SDC1, SYND1

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Galerie de données de validation

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  WB analysis of BxPC-3 using 60185-1-Ig (same clone as 60185-1-PBS)

  BxPC-3 cells were subjected to SDS PAGE followed by western blot with 60185-1-Ig (CD138/Syndecan-1 antibody) at dilution of 1:400 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 60185-1-PBS in a different storage buffer formulation.

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  Sandwich ELISA standard curve of MP50044-1

  Sandwich ELISA standard curve of MP50044-1, SDC1,CD138 Monoclonal Matched Antibody Pair, PBS Only. Capture antibody: 60185-1-PBS. Detection antibody: 67155-1-PBS. Standard: Ag17733. Range: 0.188-12 ng/mL.

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  Sample test of MP50044-1

  Plasma of sixteen individual healthy human donors was measured. The CD138/Syndecan-1 concentration of detected samples was determined to be 293.79 ng/mL with a range of 89.65-474.60 ng/mL.

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Informations sur le produit

60185-1-PBS cible CD138/Syndecan-1 dans les applications de WB, Sandwich ELISA, Indirect ELISA, Sample test et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: CD138/Syndecan-1 Protéine recombinante Ag0823
• Nom complet: syndecan 1
• Masse moléculaire calculée: 32.5 kDa
• Poids moléculaire observé: 120 kDa
• Numéro d’acquisition GenBank: BC008765
• Symbole du gène: CD138
• Identification du gène (NCBI): 6382
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine G
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Syndecan-1 (SDC1), also named CD138, is an integral membrane protein. It participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a heparan sulfate proteoglycan expressed on the surface of, and actively shed by, myeloma cells. Altered syndecan-1 expression has been detected in several different tumor types. SDC1 was regarded as a useful marker for labeling normal and neoplastic plasma cells and plasmacytoid lymphomas.

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