Anticorps Recombinant de lapin anti-CD138/Syndecan-1

CD138/Syndecan-1 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241278C7

N° de cat : 98152-1-PBS

Synonymes

Syndecan-1, Synd-1, SYND1, Sdc1, CD138

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Galerie de données de validation

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  FC experiment of mouse bone marrow cells using 98152-1-RR (same clone as 98152-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD138/Syndecan-1 Rabbit Recombinant Antibody (98152-1-RR, Clone:241278C7) or Isotype Control, and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Mouse CD19 (1D3) (CL647-65290, Clone: 1D3). Cells were not fixed. This data was developed using the same antibody clone with 98152-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse bone marrow cells using 98152-1-RR (same clone as 98152-1-PBS)

  1x10^6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD138/Syndecan-1 Rabbit Recombinant Antibody (98152-1-RR, Clone:241278C7) (red) or Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98152-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98152-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98152-1-RR against Mouse CD138/Syndecan-1 were performed. The affinity constant is 16.5 nM.

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Informations sur le produit

98152-1-PBS cible CD138/Syndecan-1 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: syndecan 1
• Masse moléculaire calculée: 33 kDa
• Numéro d’acquisition GenBank: NM_011519.2
• Symbole du gène: Sdc1
• Identification du gène (NCBI): 20969
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD138, also named as Syndecan-1 (SDC1), is an integral membrane protein. It participates in cell proliferation, cell migration and cell-matrix interactions via its receptor for extracellular matrix proteins. It is a heparan sulfate proteoglycan expressed on the surface of, and actively shed by, myeloma cells. Altered syndecan-1 expression has been detected in several different tumor types. CD138 was regarded as a useful marker for labeling normal and neoplastic plasma cells and plasmacytoid lymphomas.

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