Anticorps Recombinant de lapin anti-CD14

CD14 Recombinant Antibody for FC

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

26IC

N° de cat : 65616-1-PBS

Synonymes

26IC, CD14 molecule, Monocyte differentiation antigen CD14, membrane-bound form, Monocyte differentiation antigen CD14, urinary form, Myeloid cell-specific leucine-rich glycoprotein

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Galerie de données de validation

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  FC experiment of human PBMCs using 65616-1-MR (same clone as 65616-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD14 (26IC) Mouse IgG2a Recombinant Antibody (65616-1-MR, Clone: 26IC) or Mouse IgG2a Isotype Control, and PE-conjugated Goat Anti-Mouse IgG. Cells were then stained with APC Anti-Human CD11b (ICRF44) (APC-65116, Clone: ICRF44). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 65616-1-PBS in a different storage buffer formulation.

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  FC experiment of human PBMCs using 65616-1-MR (same clone as 65616-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD14 (26IC) Mouse IgG2a Recombinant Antibody (65616-1-MR, Clone:26IC) (red) or Mouse IgG2a Isotype Control (blue), and PE-conjugated Goat Anti-Mouse IgG. Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 65616-1-PBS in a different storage buffer formulation.

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Informations sur le produit

65616-1-PBS cible CD14 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: s/o
• Nom complet: CD14 molecule
• Masse moléculaire calculée: 375 aa, 40 kDa
• Numéro d’acquisition GenBank: BC010507
• Symbole du gène: CD14
• Identification du gène (NCBI): 929
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD14 is a 50-55 kDa glycosylphosphatidylinositol-anchored glycoprotein preferentially expressed on monocytes and macrophages, and at lower levels on granulocytes (PMID: 3385210; 2462937; 7685797). CD14 can also exist as a soluble protein. CD14 acts as a co-receptor for bacterial liposaccharides (LPS) (PMID: 1698311). It plays a major role in the inflammatory response of monocytes to LPS.

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