Anticorps Recombinant de lapin anti-CD147

CD147 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241852B4

N° de cat : 98229-1-PBS

Synonymes

241852B4, Basic immunoglobulin superfamily, Basigin, Bsg, HT7 antigen

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Galerie de données de validation

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  FC experiment of mouse thymocytes using 98229-1-RR (same clone as 98229-1-PBS)

  1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse CD147 Rabbit RecAb (98229-1-RR, Clone: 241852B4) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98229-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse thymocytes using 98229-1-RR (same clone as 98229-1-PBS)

  1x10^6 mouse thymocytes were surface stained with 0.25 ug Anti-Mouse CD147 Rabbit RecAb (98229-1-RR, Clone: 241852B4) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98229-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98229-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98229-1-RR against Mouse CD147 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

98229-1-PBS cible CD147 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD147 Protéine recombinante Eg1530
• Nom complet: basigin
• Masse moléculaire calculée: 42 kDa
• Numéro d’acquisition GenBank: NM_009768.2
• Symbole du gène: CD147
• Identification du gène (NCBI): 12215
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD147, also known as Basigin or extracellular matrix metalloproteinase inducer (EMMPRIN), is a transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 7812975). The molecule is composed of an intracellular portion, an extracellular portion and a single transmembrane region. CD147 is expressed on a variety of cell types (e.g., hematopoietic, epithelial, and endothelial cells) and at varying levels (PMID: 32968061). CD147 is a pleiotropic molecule that plays an important role in fetal, neuronal, lymphocyte and extracellular matrix development (PMID: 17945211).

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