Anticorps Recombinant de lapin anti-CD15

CD15 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

252342A1

N° de cat : 98616-1-PBS

Synonymes

Lewis X, SSEA-1

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Galerie de données de validation

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  FC experiment of human peripheral blood leukocytes using 98616-1-RR (same clone as 98616-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD15 Rabbit RecAb (98616-1-RR, Clone: 252342A1) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98616-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98616-1-RR (same clone as 98616-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD15 Rabbit RecAb (98616-1-RR, Clone: 252342A1) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 98616-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98616-1-PBS cible CD15 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: unknow
• Nom complet: CD15
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD15, also known as stage-specific embryonic antigen-1 (SSEA-1) or Lewis X (LeX), is a cell surface glycan consisting of a trisaccharide with the structure Galβ1-4[Fucα1-3]GlcNAc (PMID: 18953356). CD15 is expressed on most terminally differentiated myeloid cells, including neutrophils, eosinophils, monocytes, macrophages, mast cells, and Langerhans cells. It has also been shown to be expressed on stem cells and progenitors in the embryonic and adult nervous system, Hodgkin's lymphoma cells, and cells from a variety of solid cancers (PMID: 19185848). CD15 acts as a ligand for selectins in transendothelial migration and is involved in phagocytosis and chemotaxis (PMID: 1362195).

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