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Anticorps Recombinant de lapin anti-CD155/PVR

CD155/PVR Recombinant Antibody for IF/ICC, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IF/ICC, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241405B2

N° de cat : 84138-1-PBS

Synonymes

PVR, 241405B2, CD155, HVED, Necl 5

Galerie de données de validation

Filter:
  • Immunofluorescence (IF) / fluorescent staining of A431 cells using CD155/PVR Recombinant antibody (84138-1-RR)

    IF Staining of A431 using 84138-1-RR (same clone as 84138-1-PBS)

    Immunofluorescent analysis of (4% PFA) fixed A431 cells using CD155/PVR antibody (84138-1-RR, Clone: 241405B2 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 84138-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 84138-1-RR

    Affinity and Kinetic Characterization of 84138-1-RR

    Biolayer interferometry (BLl) kinetic assays of 84138-1-RR against Human CD155/PVR were performed. The affinity constant is 1.00 nM.

Informations sur le produit

84138-1-PBS cible CD155/PVR dans les applications de IF/ICC, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène CD155/PVR Protéine recombinante Eg0971
Nom complet poliovirus receptor
Masse moléculaire calculée 45 kDa
Numéro d’acquisition GenBankBC015542
Symbole du gène CD155/PVR
Identification du gène (NCBI) 5817
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD155, also known as PVR, is a type I transmembrane glycoprotein in the immunoglobulin superfamily. It contains three extracellular immunoglobulin-like domains, D1-D3, of which D1 is recognized by the virus. Mature human CD155 consists of a 323 amino acid extracellular domain with one N-terminal V-type and two C2-type Ig-like domains, a 24 amino acid transmembrane segment, and a 50 amino acid cytoplasmic tail. CD155 is thought to play a role in adhesion by interaction with the ECM component vitronectin as well as a role in NK killing of tumor cells. CD155 binds to two receptors of NK cells, CD96 and CD226, and accumulates at cell-cell contact sites, leading to the formation of mature immune synapses between NK cells and target cells. CD155 serves as the entry receptor for poliovirus and thereby mediates human susceptibility to poliovirus infection.

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