Anticorps Recombinant de lapin anti-CD155/PVR

CD155/PVR Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

240731B1

N° de cat : CL647-98077

Synonymes

Pvr, 240731B1, CD155, poliovirus receptor, Tage4

---

Galerie de données de validation

• 

  FC experiment of mouse thymocytes using CL647-98077

  1x10^6 mouse thymocytes were surface stained with 0.25 ug CoraLite® Plus 647 Anti-Mouse CD155/PVR Rabbit RecAb (CL647-98077, Clone: 240731B1) or 0.25 ug CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9). Cells were not fixed.

• 

  FC experiment of mouse thymocytes using CL647-98077

  1x10^6 mouse thymocytes were surface stained with 0.25 ug CoraLite® Plus 647 Anti-Mouse CD155/PVR Rabbit RecAb (CL647-98077, Clone: 240731B1) (red) or 0.25 ug CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9) (blue). Cells were not fixed.

---

Applications testées

• Résultats positifs en cytométrie: thymocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-98077 cible CD155/PVR dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD155/PVR Protéine recombinante Eg0903
• Nom complet: poliovirus receptor
• Masse moléculaire calculée: 45 kDa
• Numéro d’acquisition GenBank: NM_027514.2
• Symbole du gène: CD155/PVR
• Identification du gène (NCBI): 52118
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD155, also known as the poliovirus receptor (PVR) or Necl-5, is one of the nectin-like family members, belonging to the Ca2+ independent immunoglobulin superfamily (IgSF) in cell adhesion molecules (PMID: 37660884). CD155 is a type I transmembrane protein composed of three extracellular immunoglobulin-like domains, a transmembrane domain, and a cytoplasmic tail. It is involved in cell-to-cell and cell-to-ECM adhesion (PMID: 32019260; 11437656). CD155 acts as a ligand for immune receptors, including TIGIT, CD96 and CD226, which are expressed on T cells and NK cells. CD155 interacts with these receptors to modulate immune responses, such as T cell activation and NK cell-mediated cytotoxicity (PMID: 37660884). CD155 serves as the entry receptor for poliovirus and thereby mediates susceptibility to poliovirus infection (PMID: 15034010).

{{ptg:RelatedPrimaryAntibodies}}