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Anticorps Recombinant de lapin anti-CD16

CD16 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

230337G12

N° de cat : 83110-1-PBS

Synonymes

Fc gamma RIII alpha, Fc gamma RIII, CD16-II, CD16a antigen, CD16A

Galerie de données de validation

Filter:
  • Western Blot (WB) analysis of human placenta tissue using CD16 Recombinant antibody (83110-1-RR)

    WB analysis of human placenta using 83110-1-RR (same clone as 83110-1-PBS)

    human placenta tissue was subjected to SDS PAGE followed by western blot with 83110-1-RR (CD16 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 83110-1-PBS in a different storage buffer formulation.

  • Affinity and Kinetic Characterization of 83110-1-RR

    Affinity and Kinetic Characterization of 83110-1-RR

    Biolayer interferometry (BLl) kinetic assays of 83110-1-RR against Human CD16 were performed. The affinity constant is 71 nM.

Informations sur le produit

83110-1-PBS cible CD16 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Recombinant
Type Anticorps
Immunogène Protéine recombinante
Nom complet Fc fragment of IgG, low affinity IIIa, receptor (CD16a)
Masse moléculaire calculée 254 aa, 29 kDa
Poids moléculaire observé55 kDa
Numéro d’acquisition GenBankBC017865
Symbole du gène CD16a
Identification du gène (NCBI) 2214
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine A
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD16 is a 50-70-kDa low affinity Fc receptor found on the surface of natural killer cells, neutrophil polymorphonuclear leukocytes, monocytes and macrophages. CD16 mediates antibody-dependent cellular cytotoxicity (ADCC) and other antibody-dependent responses, such as phagocytosis. CD16 has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and FCGR3B.

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