Anticorps Recombinant de lapin anti-CD160

CD160 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241415F2

N° de cat : 98111-1-RR

Synonymes

NK1, CD160 molecule, CD160 antigen, soluble form, CD160 antigen, BY55

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Galerie de données de validation

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  FC experiment of human peripheral blood leukocytes using 98111-1-RR

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD160 Rabbit Recombinant Antibody (98111-1-RR, Clone: 241415F2) (right) or 0.25 ug Isotype Control (left) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98111-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98111-1-RR against Human CD160 were performed. The affinity constant is 1.81 nM.

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Applications testées

• Résultats positifs en cytométrie: human peripheral blood leukocytes

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98111-1-RR cible CD160 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD160 molecule
• Masse moléculaire calculée: 20 kDa
• Numéro d’acquisition GenBank: BC014465
• Symbole du gène: CD160
• Identification du gène (NCBI): 11126
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CD160 is a glycosylphosphatidylinositol (GPI)-anchored protein that is expressed on almost all intestinal intraepithelial lymphocytes (IELs), gamma delta T cells, CD56 (dim) CD16+ cytotoxic NK cells, and a minor subset of CD4+ and CD8+ T cells (PMID: 31332204; 25179432). The binding of CD160 to both classical and non-classical MHC I enhances NK and CD8+ cytotoxic T lymphocyte functions (PMID: 25179432). CD160 is a ligand for HVEM (herpes virus entry mediator) and the binding of CD160 to HVEM inhibits T cell activity (PMID: 19426226).

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