Anticorps Recombinant de lapin anti-CD164

CD164 Recombinant Antibody for WB, IF/ICC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, IF/ICC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

242986G5

N° de cat : 85723-4-PBS

Synonymes

Endolyn, MGC-24, MGC-24v, MUC-24, Multi-glycosylated core protein 24

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Galerie de données de validation

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  WB analysis of mouse liver using 85723-4-RR (same clone as 85723-4-PBS)

  mouse liver tissue was subjected to SDS PAGE followed by western blot with 85723-4-RR (CD164 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 85723-4-PBS in a different storage buffer formulation.

• 

  IF Staining of RM-1 using 85723-4-RR (same clone as 85723-4-PBS)

  Immunofluorescent analysis of (4% PFA) fixed RM-1 cells using CD164 antibody (85723-4-RR, Clone: 242986G5 ) at dilution of 1:400 and CoraLite®488-Conjugated Goat Anti-Rabbit IgG(H+L) (SA00013-2). This data was developed using the same antibody clone with 85723-4-PBS in a different storage buffer formulation.

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Informations sur le produit

85723-4-PBS cible CD164 dans les applications de WB, IF/ICC, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD164 Protéine recombinante Eg2645
• Nom complet: CD164 antigen
• Masse moléculaire calculée: 21 kDa
• Poids moléculaire observé: 80 kDa
• Numéro d’acquisition GenBank: NM_016898.2
• Symbole du gène: Cd164
• Identification du gène (NCBI): 53599
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

Sialomucins are a heterogeneous group of secreted or membrane-associated mucins that appear to play 2 key but opposing roles in vivo: first as cytoprotective or antiadhesive agents, and second as adhesion receptors. CD164 is a type I integral transmembrane sialomucin that functions as an adhesion receptor (PMID: 9680353)(PMID: 17077324). Sialomucin CD164 (MUC-24), also referred to multi-glycosylated core protein 24 (MGC24), is known to function as a receptor that regulates stem cell localization to the bone marrow. CD164 may play a key role in hematopoiesis by facilitating the adhesion of CD34+ cells to the stroma and by negatively regulating CD34+CD38(lo/-) cell proliferation. Important role of CD164 in in prostate cancer metastasis, promoting myogenesis and regulating myoblast migration so far have been revealed (PMID: 9763543)(PMID: 16859559)(PMID: 17077324).

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