Anticorps Recombinant de lapin anti-CD16b

CD16b Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241713E3

N° de cat : 98192-1-PBS

Synonymes

CD16, FCGR3B, 241713E3, Fc gamma RIII, Fc gamma RIII beta

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Galerie de données de validation

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  FC experiment of human peripheral blood leukocytes using 98192-1-RR (same clone as 98192-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD16b Rabbit Recombinant Antibody (98192-1-RR, Clone:241713E3) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98192-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human peripheral blood leukocytes using 98192-1-RR (same clone as 98192-1-PBS)

  1x10^6 human peripheral blood leukocytes were surface stained with 0.25 ug Anti-Human CD16b Rabbit Recombinant Antibody (98192-1-RR, Clone:241713E3) (red) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) (blue), and PE-conjugated Goat Anti-Rabbit IgG. Cells were not fixed. This data was developed using the same antibody clone with 98192-1-PBS in a different storage buffer formulation.

• 

  Affinity and Kinetic Characterization of 98192-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98192-1-RR against Human CD16b were performed. The affinity constant is 2.36 nM.

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Informations sur le produit

98192-1-PBS cible CD16b dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD16b Protéine recombinante Eg2487
• Nom complet: Fc fragment of IgG, low affinity IIIb, receptor (CD16b)
• Symbole du gène: FCGR3B
• Identification du gène (NCBI): 2215
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD16 is a low affinity Fc receptor. It has been identified as Fc receptors FcγRIIIa (CD16a) and FcγRIIIb (CD16b), encoded by two nearly identical genes, FCGR3A and FCGR3B. In humans, FcγRIIIa/CD16a is a type I transmembrane receptor expressed on macrophages and NK cells. FcγRIIIb/CD16b is a GPI-linked Fc-receptor highly expressed on neutrophils. The two proteins differ by only four amino acid residues in the mature proteins (PMID: 30361439).

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