Anticorps Recombinant de lapin anti-CD177

CD177 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

250745B9

N° de cat : 86454-1-PBS

Synonymes

CD177 antigen

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Galerie de données de validation

• 

  WB analysis of mouse bone marrow using 86454-1-RR (same clone as 86454-1-PBS)

  mouse bone marrow tissue was subjected to SDS PAGE followed by western blot with 86454-1-RR (Cd177 antibody) at dilution of 1:2000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 86454-1-PBS in a different storage buffer formulation.

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Informations sur le produit

86454-1-PBS cible CD177 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD177 Protéine recombinante Eg2668
• Nom complet: CD177 antigen
• Masse moléculaire calculée: 87 kDa
• Poids moléculaire observé: 130 kDa
• Numéro d’acquisition GenBank: NM_026862.3
• Symbole du gène: Cd177
• Identification du gène (NCBI): 68891
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD177, also known as NB1, HNA-2a or PRV-1, is a glycosylphosphatidylinositol (GPI)-anchored glycoprotein that belongs to the uPAR/CD59/Ly6 snake toxin superfamily (PMID: 17898576). It is expressed exclusively by neutrophils, neutrophilic metamyelocytes, and myelocytes (PMID: 17580308). CD177 interacts with β2 integrin CD11b/CD18 and CD11a/CD18, PECAM-1, and participates in neutrophil activation and transmigration (PMID: 17580308; 21193407). CD177 has been identified as a useful biomarker for myeloproliferative diseases (PMID: 17898576).

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