Anticorps Recombinant de lapin anti-CD178 (Fas ligand)

CD178 (Fas ligand) Recombinant Antibody for FC

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

NOK-1

N° de cat : 65598-1-MR

Synonymes

CD178, Fas ligand, FASLG, CD95-L, CD95L

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 65598-1-MR

  1x10^6 HEK-293T cells or CD178 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human CD178 (Fas ligand) (NOK-1) Mouse IgG2a RecAb (65598-1-MR, Clone: NOK-1) and PE-conjugated Goat Anti-Mouse IgG. Cells were not fixed.

• 

  FC experiment of Transfected HEK-293T using 65598-1-MR

  1x10^6 HEK-293T cells or CD178 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human CD178 (Fas ligand) (NOK-1) Mouse IgG2a RecAb (65598-1-MR, Clone: NOK-1) and PE-conjugated Goat Anti-Mouse IgG (red), or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: Transfected HEK-293T cells,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65598-1-MR cible CD178 (Fas ligand) dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: L5178Y mouse T lymphoma cells expressing recombinant human FasL
• Nom complet: Fas ligand (TNF superfamily, member 6)
• Masse moléculaire calculée: 281 aa, 31 kDa
• Numéro d’acquisition GenBank: BC017502
• Symbole du gène: Fas Ligand
• Identification du gène (NCBI): 356
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Stable for one year after shipment.

Informations générales

CD178, also known as Fas ligand, is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. It is expressed on NK cells, cytotoxic T lymphocytes and activated CD4+ Th1 cells. CD178 transduces apoptotic signal into cells by binding to FAS/CD95. It is involved as a death factor in the regulation of activation-induced cell death, establishment of immune privilege and tumor cell survival.

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