Anticorps Recombinant de lapin anti-CD178 (Fas ligand)

CD178 (Fas ligand) Recombinant Antibody for FC

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

NOK-1

N° de cat : 65598-1-PBS

Synonymes

CD178, Fas ligand, FASLG, CD95-L, CD95L

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 65598-1-MR (same clone as 65598-1-PBS)

  1x10^6 HEK-293T cells or CD178 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human CD178 (Fas ligand) (NOK-1) Mouse IgG2a RecAb (65598-1-MR, Clone: NOK-1) and PE-conjugated Goat Anti-Mouse IgG. Cells were not fixed. This data was developed using the same antibody clone with 65598-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 65598-1-MR (same clone as 65598-1-PBS)

  1x10^6 HEK-293T cells or CD178 transfected HEK-293T cells were surface stained with 0.25 ug Anti-Human CD178 (Fas ligand) (NOK-1) Mouse IgG2a RecAb (65598-1-MR, Clone: NOK-1) and PE-conjugated Goat Anti-Mouse IgG (red), or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4) (blue). Cells were not fixed. This data was developed using the same antibody clone with 65598-1-PBS in a different storage buffer formulation.

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Informations sur le produit

65598-1-PBS cible CD178 (Fas ligand) dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: L5178Y mouse T lymphoma cells expressing recombinant human FasL
• Nom complet: Fas ligand (TNF superfamily, member 6)
• Masse moléculaire calculée: 281 aa, 31 kDa
• Numéro d’acquisition GenBank: BC017502
• Symbole du gène: Fas Ligand
• Identification du gène (NCBI): 356
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD178, also known as Fas ligand, is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) family. It is expressed on NK cells, cytotoxic T lymphocytes and activated CD4+ Th1 cells. CD178 transduces apoptotic signal into cells by binding to FAS/CD95. It is involved as a death factor in the regulation of activation-induced cell death, establishment of immune privilege and tumor cell survival.

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