Anticorps Recombinant de lapin anti-CD18

CD18 Recombinant Antibody for FC

Hôte / Isotype

Rat / IgG2a

Réactivité testée

souris

Applications

FC

Conjugaison

FITC Plus Fluorescent Dye

CloneNo.

M18/2

N° de cat : FITC-65671

Synonymes

Itgb2, integrin beta 2, LAD, LCAMB, Lfa1

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Galerie de données de validation

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  FC experiment of mouse thymocytes using FITC-65671

  1x10^6 mouse thymocytes were surface stained with 0.25 ug FITC Plus Anti-Mouse CD18 (M18/2) Rat IgG2a RecAb (FITC-65671, Clone: M18/2) or FITC Plus Rat IgG2a Isotype Control (2A3) (FITC-65209, Clone: 2A3). Cells were not fixed.

• 

  FC experiment of mouse thymocytes using FITC-65671

  1x10^6 mouse thymocytes were surface stained with 0.25 ug FITC Plus Anti-Mouse CD18 (M18/2) Rat IgG2a RecAb (FITC-65671, Clone: M18/2) (red) or FITC Plus Rat IgG2a Isotype Control (2A3) (FITC-65209, Clone: 2A3) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: thymocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

FITC-65671 cible CD18 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Rat / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: s/o
• Nom complet: integrin beta 2
• Numéro d’acquisition GenBank: BC145644
• Symbole du gène: CD18
• Identification du gène (NCBI): 16414
• Conjugaison: FITC Plus Fluorescent Dye
• Excitation/Emission maxima wavelengths: 495 nm / 524 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD18, also known as integrin beta-2, is a transmembrane protein that forms heterodimers with CD11a, CD11b, CD11c, CD11d (PMID: 1968349). CD11a/CD18 (LFA-1) is expressed by all leukocytes, while CD11b/CD18 (Mac-1) and CD11c/CD18 (p150,95) are normally restricted to expression on monocytes, macrophages, polymorphonuclear lymphocytes (PMNs), and natural killer cells (PMID: 1968349; 3109455; 10946284). CD18 plays an important role in mediating cell adhesion during immune response and defects of CD18 cause leukocyte adhesion deficiency (PMID: 3594570).

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