Anticorps Recombinant de lapin anti-CD19

CD19 Recombinant Antibody for FC

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Lapin

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242570A11

N° de cat : 98351-1-MR

Synonymes

CD19 molecule

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Galerie de données de validation

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  FC experiment of rabbit splenocytes using 98351-1-MR

  1x10^6 rabbit splenocytes were surface stained with 0.25 ug Anti-Rabbit CD19 Mouse RecAb (98351-1-MR, Clone:242570A11) .or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4)and PE-conjugated Goat Anti-Mouse IgG. Cells were then stained with Anti-Rabbit FITC-CD4. Cells were not fixed.

• 

  FC experiment of rabbit splenocytes using 98351-1-MR

  1x10^6 rabbit splenocytes were surface stained with 0.25 ug Anti-Rabbit CD19 Mouse RecAb (98351-1-MR, Clone:242570A11)(red).or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4)and PE-conjugated Goat Anti-Mouse IgG(blue). Cells were not fixed.

• 

  FC experiment of rabbit splenocytes using 98351-1-MR

  1x10^6 rabbit splenocytes were surface stained with 0.25 ug Anti-Rabbit CD19 Mouse RecAb (98351-1-MR, Clone:242570A11).or Mouse IgG2a Isotype Control (C1.18.4) (65208-1-Ig, Clone: C1.18.4)and PE-conjugated Goat Anti-Mouse IgG. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: rabbit splenocytes

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98351-1-MR cible CD19 dans les applications de FC et montre une réactivité avec des échantillons Lapin

• Réactivité: Lapin
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD19 Protéine recombinante Eg3526
• Nom complet: CD19
• Symbole du gène: CD19
• Identification du gène (NCBI): 100345233
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908).

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