Anticorps Recombinant de lapin anti-CD19

CD19 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

APC-Cyanine7 Fluorescent Dye

CloneNo.

242301C6

N° de cat : AY7-98287

Synonymes

242301C6, CD19 antigen

---

Galerie de données de validation

• 

  FC experiment of mouse splenocytes using AY7-98287

  1x10^6 mouse splenocytes were surface stained with 0.1 ug CoraLite® Plus 488 Anti-Mouse CD3 (17A2) (CL488-65077, Clone: 17A2), and 0.1 ug APC-Cyanine7 Anti-Mouse CD19 Rabbit RecAb (AY7-98287, Clone: 242301C6) or unstained. Cells were not fixed.

• 

  FC experiment of mouse splenocytes using AY7-98287

  1x10^6 mouse splenocytes were surface stained with 0.1 ug APC-Cyanine7 Anti-Mouse CD19 Rabbit RecAb (AY7-98287, Clone:242301C6) (red) or unstained (blue). Cells were not fixed.

---

Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

AY7-98287 cible CD19 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD19 Protéine recombinante Eg3194
• Nom complet: CD19 antigen
• Masse moléculaire calculée: 60 kDa
• Numéro d’acquisition GenBank: NM_009844.2
• Symbole du gène: Cd19
• Identification du gène (NCBI): 12478
• Conjugaison: APC-Cyanine7 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 650 nm / 778 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD19 is a 95 kDa type I transmembrane glycoprotein belonging to the immunoglobulin superfamily (PMID: 2472450). It is expressed by B cells and follicular dendritic cells. CD19 is up-regulated at the step of B-lineage commitment during the differentiation of the hematopoietic stem cell, it remains on during subsequent stages of differentiation until finally down-regulated during terminal differentiation into plasma cells (PMID: 8528044). CD19 is involved in B cell development, activation and differentiation. It is the dominant component for the signaling complex on B cells that includes CD21 (CR2), CD81 (TAPA-1) and CD225 and acts as a critical co-receptor for BCR signal transduction (PMID: 23210908).

{{ptg:RelatedPrimaryAntibodies}}