Anticorps Recombinant de lapin anti-CD2

CD2 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

241222E2

N° de cat : 98134-1-PBS

Synonymes

241222E2, CD2 molecule, Erythrocyte receptor, LFA 2, LFA 3 receptor

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Galerie de données de validation

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  FC experiment of human PBMCs using 98134-1-RR (same clone as 98134-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD2 Rabbit RecAb (98134-1-RR, Clone: 241222E2) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were co-stained with CoraLite® Plus 647 Anti-Human CD3 (OKT3) Mouse IgG2a Recombinant Antibody (CL647-65569, Clone: OKT3). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98134-1-PBS in a different storage buffer formulation.

• 

  FC experiment of human PBMCs using 98134-1-RR (same clone as 98134-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD2 Rabbit RecAb (98134-1-RR, Clone: 241222E2) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. Lymphocytes were gated. This data was developed using the same antibody clone with 98134-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98134-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98134-1-RR against Human CD2 were performed. The affinity constant is 0.418 nM.

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Informations sur le produit

98134-1-PBS cible CD2 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD2 Protéine recombinante Eg1271
• Nom complet: CD2 molecule
• Masse moléculaire calculée: 351 aa, 39 kDa
• Numéro d’acquisition GenBank: BC033583
• Symbole du gène: CD2
• Identification du gène (NCBI): 914
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD2 is a cell surface glycoprotein present on a majority of thymocytes, all mature T cells and subset of NK cells but not on B lymphocytes. It is a pan T-cell marker. CD2 interacts with lymphocyte function-associated antigen (LFA-3/CD58) and CD48/BCM1 to mediate adhesion between T-cells and other cell types. CD2 is implicated in the triggering of T-cells, the cytoplasmic domain is implicated in the signaling function.

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