Anticorps Monoclonal anti-CD20

CD20 Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG2b, kappa

Réactivité testée

Humain

Applications

FC

Conjugaison

Atlantic Blue™ Fluorescent Dye

CloneNo.

2H7

N° de cat : AB-65085

Synonymes

B lymphocyte antigen CD20, B1, Bp35, CD20, LEU 16, MS4A1, MS4A1,CD20, MS4A2, S7



Applications testées

Résultats positifs en cytométrieCMSP humaines,

Dilution recommandée

ApplicationDilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 μl per 10^6 cells in a 100 µl suspension or 5 μl per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

AB-65085 cible CD20 dans les applications de FC et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG2b, kappa
Clonalité Monoclonal
Type Anticorps
Immunogène Lymphocytes B amygdaliennes humaines
Nom complet membrane-spanning 4-domains, subfamily A, member 1
Masse moléculaire calculée 297 aa, 33 kDa
Numéro d’acquisition GenBankBC002807
Symbole du gène MS4A1
Identification du gène (NCBI) 931
Conjugaison Atlantic Blue™ Fluorescent Dye
Excitation/Emission maxima wavelengths404 nm / 458 nm
Forme Liquide
Méthode de purification Purification par affinité
Tampon de stockage PBS with 0.09% sodium azide and 0.5% BSA.
Conditions de stockageStore at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD20 is a 33-37 kDa transmembrane phosphoprotein belonging to the membrane-spanning 4A family (PMID: 3260267; 16785532). CD20 is a B-lymphocyte surface molecule that is widely expressed during B-cell ontogeny, from early pre-B-cell developmental stages until final differentiation into plasma cells (PMID: 7524522). CD20 functions as calcium-permeable cation channel (PMID: 7684739). It is involved in the regulation of B-cell activation, proliferation and differentiation (PMID: 7524522).

Protocole

Product Specific Protocols
FC protocol for Atlantic Blue™ CD20 antibody AB-65085Download protocol
Standard Protocols
Click here to view our Standard Protocols