Anticorps Monoclonal anti-CD200

CD200 Monoclonal Antibody for FC

Hôte / Isotype

Rat / IgG2a, kappa

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

OX90

N° de cat : 65230-1-Ig

Synonymes

Cd200, CD200 antigen, Mox2, OX2

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 65230-1-Ig

  1x10^6 mouse splenocytes were surface stained with 1 ug Anti-Mouse CD200 (65230-1-Ig, Clone: OX90) and FITC anti-rat IgG2a Antibody at dilution 1:100 (red), or 1 ug Rat IgG2a Isotype Control (2A3) (65209-1-Ig, Clone: 2A3) and FITC anti-rat IgG2a Antibody at dilution 1:100 (blue). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 65230-1-Ig

  1x10^6 mouse splenocytes were surface stained with 1 ug Anti-Mouse CD200 (65230-1-Ig, Clone: OX90) and FITC anti-rat IgG2a Antibody at dilution 1:100, or 1 ug Rat IgG2a Isotype Control (2A3) (65209-1-Ig, Clone: 2A3) and FITC anti-rat IgG2a Antibody at dilution 1:100. Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

65230-1-Ig cible CD200 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Rat / IgG2a, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: Mouse CD200-rat CD4 fusion protein
• Nom complet: CD200 antigen
• Numéro d’acquisition GenBank: BC051984
• Symbole du gène: Cd200
• Identification du gène (NCBI): 17470
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Stable for one year after shipment.

Informations générales

CD200, also known as OX2, is a type I transmembrane glycoprotein that belongs to the immunoglobulin superfamily (PMID: 3032785). It contains two extracellular immunoglobulin domains, a transmembrane and a cytoplasmic domain. CD200 is expressed on a variety of cell types, including thymocytes, B lymphocytes, a subset of T lymphocytes, follicular dendritic cells, neurons, and endothelial cells (PMID: 3032785; 10981966). CD200 binds to its receptor, CD200R, which is primarily expressed by myeloid and T cell lineage (PMID: 15187158). The CD200-CD200R interaction plays a role in immunosuppression and suppression of anti-tumor immune responses (PMID: 22020332).

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