Anticorps Recombinant de lapin anti-CD209

CD209 Recombinant Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

240907A2

N° de cat : 84095-6-PBS

Synonymes

DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN

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Galerie de données de validation

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  WB analysis of human placenta using 84095-6-RR (same clone as 84095-6-PBS)

  human placenta tissue was subjected to SDS PAGE followed by western blot with 84095-6-RR (CD209 antibody) at dilution of 1:5000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84095-6-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84095-6-RR

  Biolayer interferometry (BLl) kinetic assays of 84095-6-RR against Human CD209 were performed. The affinity constant is below 1 pM.

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Informations sur le produit

84095-6-PBS cible CD209 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD209 molecule
• Masse moléculaire calculée: 404 aa, 45.7 kDa
• Poids moléculaire observé: 48 kDa
• Numéro d’acquisition GenBank: BC110615
• Symbole du gène: CD209
• Identification du gène (NCBI): 30835
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).

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