Anticorps Recombinant de lapin anti-CD209

CD209 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240907A4

N° de cat : 98156-1-RR

Synonymes

DC SIGN1, DC SIGN, C-type lectin domain family 4 member L, CLEC4L, CDSIGN

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Galerie de données de validation

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  FC experiment of human monocyte-derived immature dendritic cells using 98156-1-RR

  1x10^6 human monocyte-derived immature dendritic cells were surface stained with 0.25 ug Anti-Human CD209 Rabbit Recombinant Antibody (98156-1-RR, Clone: 240907A4) (red) or 0.25 ug Isotype Control (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98156-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98156-1-RR against Human CD209 were performed. The affinity constant is 1.94 nM.

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Applications testées

• Résultats positifs en cytométrie: human monocyte-derived immature dendritic cells,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98156-1-RR cible CD209 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD209 molecule
• Masse moléculaire calculée: 404 aa, 45.7 kDa
• Numéro d’acquisition GenBank: BC110615
• Symbole du gène: CD209
• Identification du gène (NCBI): 30835
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).

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