Anticorps Recombinant de lapin anti-CD209

CD209 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

PE Fluorescent Dye

CloneNo.

240907A4

N° de cat : PE-FcA98156

Synonymes

CDSIGN, CLEC4L, C-type lectin domain family 4 member L, DC SIGN, DC SIGN1

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Galerie de données de validation

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  FC experiment of human monocyte-derived immature dendritic cells using PE-FcA98156

  1x10^6 human monocyte-derived immature dendritic cells were surface stained with 5 ul PE Anti-Human CD209 Rabbit RecAb (PE-FcA98156, Clone: 240907A4) (red) or PE Rabbit IgG Isotype Control RecAb (PE-FcA98136, Clone: 240953C9) (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: human monocyte-derived immature dendritic cells,

Dilution recommandée

Application	Dilution
This reagent has been pre-titrated and tested for flow cytometric analysis. The suggested use of this reagent is 5 ul per 10^6 cells in a 100 µl suspension or 5 ul per 100 µl of whole blood.
Sample-dependent, check data in validation data gallery

Informations sur le produit

PE-FcA98156 cible CD209 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD209 Protéine recombinante Eg0062
• Nom complet: CD209 molecule
• Masse moléculaire calculée: 404 aa, 45.7 kDa
• Numéro d’acquisition GenBank: BC110615
• Symbole du gène: CD209
• Identification du gène (NCBI): 30835
• Conjugaison: PE Fluorescent Dye
• Excitation/Emission maxima wavelengths: 496 nm, 565 nm / 578 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide and 0.5% BSA
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD209 (DC-SIGN, CLEC4L) is a C-type lectin receptor that is involved in the innate immune system and recognizes numerous evolutionarily divergent pathogens, including bacteria, viruses, and parasites. CD209 is preferentially expressed on dendritic cells (DCs). It mediates transient adhesion of DCs with T cells. It has been reported that CD209 plays a role in capture and transmission of HIV from DC to T cells (PMID: 10721995).

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