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Anticorps Monoclonal anti-CD226

CD226 Monoclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Mouse / IgG1

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

7G7A4

N° de cat : 67653-1-PBS

Synonymes

CD226, CD226 antigen, CD226 molecule, DNAM 1, DNAM1, DNAX accessory molecule 1, PTA1, TLiSA1

Galerie de données de validation

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  • Western Blot (WB) analysis of human peripheral blood platelets using CD226 Monoclonal antibody (67653-1-Ig)

    WB analysis of human peripheral blood platelets using 67653-1-Ig (same clone as 67653-1-PBS)

    human peripheral blood platelets were subjected to SDS PAGE followed by western blot with 67653-1-Ig (CD226 antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 67653-1-PBS in a different storage buffer formulation.

Informations sur le produit

67653-1-PBS cible CD226 dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Mouse / IgG1
Clonalité Monoclonal
Type Anticorps
Immunogène CD226 Protéine recombinante Ag12403
Nom complet CD226 molecule
Masse moléculaire calculée 336 aa, 39 kDa
Poids moléculaire observé 65 kDa
Numéro d’acquisition GenBankBC074787
Symbole du gène CD226
Identification du gène (NCBI) 10666
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par protéine G
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).

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