Anticorps Recombinant de lapin anti-CD226

CD226 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250384G1

N° de cat : 98495-1-PBS

Synonymes

CD226 antigen, Dnam-1 , Platelet and T-cell activation antigen 1, Pta1

---

Galerie de données de validation

• 

  FC experiment of mouse splenocytes using 98495-1-RR (same clone as 98495-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD226 Rabbit RecAb (98495-1-RR, Clone: 250384G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Mouse CD8a. Cells were not fixed. This data was developed using the same antibody clone with 98495-1-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 98495-1-RR (same clone as 98495-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD226 Rabbit RecAb (98495-1-RR, Clone: 250384G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98495-1-PBS in a different storage buffer formulation.

---

Informations sur le produit

98495-1-PBS cible CD226 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD226 Protéine recombinante Eg1588
• Nom complet: CD226 antigen
• Masse moléculaire calculée: 39 kDa
• Numéro d’acquisition GenBank: NM_178687.2
• Symbole du gène: Cd226
• Identification du gène (NCBI): 225825
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).

{{ptg:RelatedPrimaryAntibodies}}