Anticorps Recombinant de lapin anti-CD226

CD226 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250384G1

N° de cat : 98495-1-RR

Synonymes

CD226 antigen, Dnam-1 , Platelet and T-cell activation antigen 1, Pta1

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98495-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD226 Rabbit RecAb (98495-1-RR, Clone: 250384G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 647 Anti-Mouse CD8a. Cells were not fixed.

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  FC experiment of mouse splenocytes using 98495-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD226 Rabbit RecAb (98495-1-RR, Clone: 250384G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98495-1-RR cible CD226 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD226 Protéine recombinante Eg1588
• Nom complet: CD226 antigen
• Masse moléculaire calculée: 39 kDa
• Numéro d’acquisition GenBank: NM_178687.2
• Symbole du gène: Cd226
• Identification du gène (NCBI): 225825
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

CD226 (DNAM-1) is a ~65 kDa glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. CD226 mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. Interactions of CD226 and its ligands, CD155 and CD112, induce NK and T cell-mediated cytotoxicity and cytokine secretion (PMID: 15039383).

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