Anticorps Polyclonal de lapin anti-CD228/MFI2

CD228/MFI2 Polyclonal Antibody for WB, ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, ELISA

Conjugaison

Non conjugué

N° de cat : 33666-1-AP

Synonymes

CD228, Melanotransferrin, Meltf, Membrane-bound transferrin-like protein p97, Mfi2

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Galerie de données de validation

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  WB analysis using 33666-1-AP

  Various lysates were subjected to SDS PAGE followed by western blot with 33666-1-AP (CD228/MFI2 antibody) at dilution of 1:500 incubated at room temperature for 1.5 hours.

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Applications testées

• Résultats positifs en WB: tissu cérébral de souris,

Dilution recommandée

• Western Blot (WB): WB : 1:500-1:1000

It is recommended that this reagent should be titrated in each testing system to obtain optimal results.

Sample-dependent, check data in validation data gallery

Informations sur le produit

33666-1-AP cible CD228/MFI2 dans les applications de WB, ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: CD228/MFI2 Protéine recombinante Eg6302
• Nom complet: antigen p97 (melanoma associated) identified by monoclonal antibodies 133.2 and 96.5
• Masse moléculaire calculée: 81 kDa
• Poids moléculaire observé: 81 kDa
• Numéro d’acquisition GenBank: NM_013900.2
• Symbole du gène: Mfi2
• Identification du gène (NCBI): 30060
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS with 0.02% sodium azide and 50% glycerol
• Conditions de stockage: Stocker à -20°C. Stable pendant un an après l'expédition. L'aliquotage n'est pas nécessaire pour le stockage à -20^oC Les 20ul contiennent 0,1% de BSA.

Informations générales

CD228, also known as Melanotransferrin (MTF), p97, MFI2, etc., is an iron-binding glycoprotein belonging to the transferrin family. In normal tissues, the expression of CD228 is low, mainly confined to skin epidermis, brain endothelium, renal tubules, sweat gland and salivary gland ducts. However, in many tumor tissues, such as melanoma, non-small cell lung cancer, colorectal cancer, pancreatic cancer and so on, the expression of CD228 increased significantly. Soluble CD228 can cross the blood-brain barrier by interacting with transferrin receptor. In the brain, CD228 is located in microglia related to amyloid plaque cells in Alzheimer's disease. The increased concentration of CD228 in serum can be regarded as a surrogate marker of Alzheimer's disease.

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