Anticorps Recombinant de lapin anti-CD229/SLAMF3

CD229/SLAMF3 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242312D12

N° de cat : 98274-1-PBS

Synonymes

Lymphocyte antigen 9, Ly-9, Ly9, Cell surface molecule Ly-9, CD229

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98274-1-RR (same clone as 98274-1-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD229/SLAMF3 Rabbit Recombinant Antibody (98274-1-RR, Clone: 242312D12) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (red), or 0.25 ug Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L) (blue). Cells were not fixed. This data was developed using the same antibody clone with 98274-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98274-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98274-1-RR against Mouse CD229/SLAMF3 were performed. The affinity constant is 2.29 nM.

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Informations sur le produit

98274-1-PBS cible CD229/SLAMF3 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: lymphocyte antigen 9
• Masse moléculaire calculée: 73 kDa
• Numéro d’acquisition GenBank: NM_001277968.1
• Symbole du gène: Ly9
• Identification du gène (NCBI): 17085
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Signaling lymphocytic activation molecule 3 (SLAMF3), also known as CD229 or Ly9, is a type I transmembrane glycoprotein that belongs to the SLAM family receptors (PMID: 10970093; 15905546). It is composed of an extracellular region, which consists of four Ig-like domains, a transmembrane region, and a cytoplasmic tail, which includes two immunoreceptor tyrosine-based signaling motifs (ITSMs) and other tyrosine residues that act as binding sites for the SH2 structural domains (PMID: 8537117; 11369645; 38626547). SLAMF3 is mainly expressed in immune cells, such as T, B, and natural killer cells, and it is involved in the fundamental activation and suppression of these immune cells, as well as the regulation of complex immune networks (PMID: 38626547).

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