Anticorps Recombinant de lapin anti-CD268/BAFF-R

CD268/BAFF-R Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

243120H8

N° de cat : 98404-1-RR

Synonymes

BAFF receptor, Baffr, BAFF-R, B-cell maturation defect, B-cell-activating factor receptor

---

Galerie de données de validation

• 

  FC experiment of mouse splenocytes using 98404-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD268/BAFF-R Rabbit RecAb (98404-1-RR, Clone: 243120H8) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-2-RR, Clone: 240953A11), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with CoraLite® Plus 488 Anti-Mouse CD19. Cells were not fixed.

• 

  FC experiment of mouse splenocytes using 98404-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD268/BAFF-R Rabbit RecAb (98404-1-RR, Clone: 243120H8) (red) or 0.25 ug Rabbit IgG Isotype Control RecAb (98136-2-RR, Clone: 240953A11) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed.

---

Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98404-1-RR cible CD268/BAFF-R dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD268/BAFF-R Protéine recombinante Eg1840
• Nom complet: tumor necrosis factor receptor superfamily, member 13c
• Masse moléculaire calculée: 19 kDa
• Numéro d’acquisition GenBank: NM_028075.2
• Symbole du gène: Tnfrsf13c
• Identification du gène (NCBI): 72049
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2 - 8°C. Stable for one year after shipment.

Informations générales

B-cell-activating factor receptor (BAFF-R, also known as CD268 and TNFRSF13C) is a member of the tumor necrosis factor receptor (TNFR) superfamily. It is expressed in most malignant B cells, including those in primary central nervous system lymphoma (PCNSL), and is involved in the survival and proliferation of these cells (PMID: 32528875). The interaction of BAFF with BAFF-R promotes NF-κB activation, which plays a crucial role in B-cell maturation, survival, and costimulation of T-cell activation and proliferation (PMID: 30349534). Additionally, BAFF-R is associated with chronic kidney disease (CKD) by activating NF-κB signaling in renal tubular epithelial cells (PMID: 38791453).

{{ptg:RelatedPrimaryAntibodies}}