Anticorps Monoclonal anti-Integrin Beta 1/CD29

Integrin Beta 1/CD29 Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgG1, kappa

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

TS2/16

N° de cat : 65191-1-PBS

Synonymes

ITGB1, CD29, FNRB, Glycoprotein IIa, GPIIA

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Galerie de données de validation

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  FC experiment of human PBMCs using 65191-1-Ig (same clone as 65191-1-PBS)

  1x10^6 human PBMCs were surface stained with 0.25 ug Anti-Human CD29 (TS2/16) (65191-1-Ig, Clone:TS2/16) or Mouse IgG1 Isotype Control (MOPC-21) (65124-1-Ig, Clone: MOPC-21), and PE-conjugated Goat Anti-Mouse IgG. Cells were then stained with CoraLite® Plus 647 Anti-Human CD45 Rabbit Recombinant Antibody (CL647-98117, Clone: 241670E10). Cells were incubated with FC Receptor Block prior to staining. Cells were not fixed. This data was developed using the same antibody clone with 65191-1-PBS in a different storage buffer formulation.

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Informations sur le produit

65191-1-PBS cible Integrin Beta 1/CD29 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG1, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: s/o
• Nom complet: integrin, beta 1 (fibronectin receptor, beta polypeptide, antigen CD29 includes MDF2, MSK12)
• Masse moléculaire calculée: 88 kDa
• Numéro d’acquisition GenBank: BC020057
• Symbole du gène: Integrin beta 1
• Identification du gène (NCBI): 3688
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

Integrin beta-1 (ITGB1), also named as CD29, is a 130 kDa single chain type I glycoprotein that is expressed in a heterodimeric complex with one of six distinct α subunits, comprising the very late activation antigen (VLA) subfamily of adhesion receptors. It is one of the essential surface molecules expressed on human MSC from bone marrow and other sources. The β1 subunit is also broadly expressed on lymphocytes and monocytes, weakly expressed on granulocytes, and not expressed on erythrocytes. These receptors are involved in a variety of cell-cell and cell-matrix interactions.

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