Anticorps Recombinant de lapin anti-CD30 Ligand/TNFSF8

CD30 Ligand/TNFSF8 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

CoraLite® Plus 647 Fluorescent Dye

CloneNo.

241012G10

N° de cat : CL647-98113

Synonymes

Tnfsf8, 241012G10, CD30 ligand, CD30-L, Tumor necrosis factor ligand superfamily member 8

---

Galerie de données de validation

• 

  FC experiment of mouse splenocytes using CL647-98113

  1x10^6 untreated or anti-CD3/CD28 treated mouse splenocytes were surface stained with CoraLite® Plus 488 Anti-Mouse CD4 and 0.25 ug CoraLite® Plus 647 Anti-Mouse CD30 Ligand/TNFSF8 Rabbit RecAb (CL647-98113, Clone: 241012G10). Cells were not fixed.

• 

  FC experiment of mouse splenocytes using CL647-98113

  1x10^6 anti-CD3/CD28 treated mouse splenocytes were surface stained with 0.25 ug CoraLite® Plus 647 Anti-Mouse CD30 Ligand/TNFSF8 Rabbit RecAb (CL647-98113, Clone: 241012G10) (red) or CoraLite® Plus 647 Rabbit IgG Isotype Control RecAb (CL647-98136, Clone: 240953C9) (blue). 1x10^6 untreated mouse splenocytes were surface stained with 0.25 ug CoraLite® Plus 647 Anti-Mouse CD30 Ligand/TNFSF8 Rabbit RecAb (CL647-98113, Clone: 241012G10) (black, dashed). Cells were not fixed.

---

Applications testées

• Résultats positifs en cytométrie: anti-CD3/CD28 treated mouse splenocytes

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

CL647-98113 cible CD30 Ligand/TNFSF8 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD30 Ligand/TNFSF8 Protéine recombinante Eg0667
• Nom complet: tumor necrosis factor (ligand) superfamily, member 8
• Masse moléculaire calculée: 27 kDa
• Numéro d’acquisition GenBank: NM_009403.3
• Symbole du gène: Tnfsf8
• Identification du gène (NCBI): 21949
• Conjugaison: CoraLite® Plus 647 Fluorescent Dye
• Excitation/Emission maxima wavelengths: 654 nm / 674 nm
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD30 Ligand (CD30L), also named as TNFSF8 or CD153, is a type II transmembrane protein that belongs to the tumor necrosis factor (TNF) superfamily (PMID: 8391931). It is expressed on the surface of activated T cells, B cells, monocytes, macrophages, eosinophils, neutrophils, and mast cells (PMID: 26090498). CD30L interacts with its receptor, CD30, which is a cell surface protein expressed on a small subset of activated T and B lymphocytes, and a variety of lymphoid neoplasms, with the highest expression in classical Hodgkin lymphoma and anaplastic large cell lymphomas (PMID: 28885612). The CD30/CD30L signaling is involved in pleiotropic downstream effects including differentiation, cell survival and death, NFkB activation, and production of cytokines (PMID: 38534788).

{{ptg:RelatedPrimaryAntibodies}}