Anticorps Recombinant de lapin anti-CD30/TNFRSF8

CD30/TNFRSF8 Recombinant Antibody for WB, IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

WB, IHC, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241710B9

N° de cat : 84420-7-PBS

Synonymes

CD30, CD30L receptor, Lymphocyte activation antigen CD30, Tnfrsf8, Tumor necrosis factor receptor superfamily member 8

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Galerie de données de validation

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  WB analysis of EL-4 using 84420-7-RR (same clone as 84420-7-PBS)

  EL-4 cells were subjected to SDS PAGE followed by western blot with 84420-7-RR (CD30/TNFRSF8 antibody) at dilution of 1:1000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 84420-7-PBS in a different storage buffer formulation.

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  IHC staining of mouse spleen using 84420-7-RR (same clone as 84420-7-PBS)

  Immunohistochemical analysis of paraffin-embedded mouse spleen tissue slide using 84420-7-RR (CD30/TNFRSF8 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84420-7-PBS in a different storage buffer formulation.

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Informations sur le produit

84420-7-PBS cible CD30/TNFRSF8 dans les applications de WB, IHC, Indirect ELISA et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD30/TNFRSF8 Protéine recombinante Eg1307
• Nom complet: tumor necrosis factor receptor superfamily, member 8
• Masse moléculaire calculée: 53kDa
• Poids moléculaire observé: 105-120 kDa
• Numéro d’acquisition GenBank: NM_009401.2
• Symbole du gène: Tnfrsf8
• Identification du gène (NCBI): 21941
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD30, also known as TNFRSF8 or Ki-1, is a transmembrane glycoprotein belonging to the tumor necrosis factor receptor superfamily. It is composed of an extracellular domain with six cysteine-rich repeats, a transmembrane segment, and an intracellular domain (PMID: 1310894). CD30 is expressed on a small subset of activated T and B lymphocytes, and a variety of lymphoid neoplasms, with the highest expression in classical Hodgkin's lymphoma and anaplastic large cell lymphoma (PMID: 9826579; 28885612). The CD30 ligand (CD30L or CD153) is a type II transmembrane glycoprotein of the tumor necrosis factor ligand superfamily (PMID: 8701986). Signal transduction of CD30/CD30L utilizes signal transducers, TNFR-associated factors (TRAF1, 2, 3 and 5) (PMID: 9826579).

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