Anticorps Polyclonal de lapin anti-CD300c

CD300c Polyclonal Antibody for IHC, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 32141-1-PBS

Synonymes

CMRF35, CMRF 35A, CMRF 35, CLM 6, CD300c molecule

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Galerie de données de validation

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  IHC staining of human tonsillitis using 32141-1-AP (same clone as 32141-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 32141-1-AP (CD300c antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32141-1-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 32141-1-AP (same clone as 32141-1-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 32141-1-AP (CD300c antibody) at dilution of 1:200 (under 20x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 32141-1-PBS in a different storage buffer formulation.

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Informations sur le produit

32141-1-PBS cible CD300c dans les applications de IHC, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Polyclonal
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD300c molecule
• Masse moléculaire calculée: 224 aa, 25 kDa
• Numéro d’acquisition GenBank: BC022279
• Symbole du gène: CD300C
• Identification du gène (NCBI): 10871
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité contre l'antigène
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD300c is a member of the CD300 family of receptors, which are type I transmembrane proteins expressed in both myeloid and lymphoid lineages and modulate immune responses by their stimulatory and inhibitory capabilities (PMID: 30485414). CD300c, also known as CLM-6, CMRF-35 and IgSF16, is composed of an IgV-like extracellular domain, a transmembrane domain and a short cytoplasmic tail. It is expressed on the surface of monocytes, macrophages, dendritic cells, neutrophils, some T and B lymphocytes (PMID: 1349532; 30498497). CD300c has been reported as an activating receptor expressed on monocytes and that it has a potential role in inflammatory responses (PMID: 23571507). It has also been identified as a T cell co-inhibitory molecule (PMID: 30498497).

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