Anticorps Recombinant de lapin anti-CD314/NKG2D

CD314/NKG2D Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

250267G1

N° de cat : 98481-2-PBS

Synonymes

CD314, Klrk1, Killer cell lectin-like receptor subfamily K member 1, NK cell receptor D, NKG2 D

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98481-2-RR (same clone as 98481-2-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD314/NKG2D Rabbit RecAb (98481-2-RR, Clone: 250267G1) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse NK1.1. Cells were not fixed. This data was developed using the same antibody clone with 98481-2-PBS in a different storage buffer formulation.

• 

  FC experiment of mouse splenocytes using 98481-2-RR (same clone as 98481-2-PBS)

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse CD314/NKG2D Rabbit RecAb (98481-2-RR, Clone: 250267G1) (red) or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue), and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were not fixed. This data was developed using the same antibody clone with 98481-2-PBS in a different storage buffer formulation.

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Informations sur le produit

98481-2-PBS cible CD314/NKG2D dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD314/NKG2D Protéine recombinante Eg3829
• Nom complet: killer cell lectin-like receptor subfamily K, member 1
• Masse moléculaire calculée: 27 kDa
• Numéro d’acquisition GenBank: NM_033078.4
• Symbole du gène: CD314
• Identification du gène (NCBI): 27007
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In mice, CD314 is expressed on NK cells, activated CD8(+) T cells and macrophages, and subsets of TCR gamma delta (+) and NK1.1 (+) T cells (PMID: 12150888). Various subfamilies of MHC class I-related glycoproteins have been identified as the ligands for mouse CD314, including RAET1A, RAET1B, RAET1C, RAET1D, RAET1E, H60 and MULT1 (PMID: 31720075).

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