Anticorps Recombinant de lapin anti-CD314/NKG2D

CD314/NKG2D Recombinant Antibody for FC

Hôte / Isotype

Mouse / IgG2a

Réactivité testée

Humain

Applications

FC

Conjugaison

Biotin

CloneNo.

1D11

N° de cat : Biotin-65643

Synonymes

KLRK1, CD314, 1D11, KLR, Killer cell lectin-like receptor subfamily K member 1

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Galerie de données de validation

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  FC experiment of human PBMCs using Biotin-65643

  1x10^6 human PBMCs were surface stained with 0.25 ug Biotin Anti-Human CD314/NKG2D (1D11) Mouse IgG2a RecAb (Biotin-65643, Clone:1D11) and CoraLite®488-conjugated streptavidin, or unstained. Cells were co-stained with CoraLite® Plus 647 Anti-Human CD8 (UCHT4) Mouse IgG2a Recombinant Antibody (CL647-65559, Clone: UCHT4). Cells were not fixed.

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  FC experiment of human PBMCs using Biotin-65643

  1x10^6 human PBMCs were surface stained with 0.25 ug Biotin Anti-Human CD314/NKG2D (1D11) Mouse IgG2a RecAb (Biotin-65643, Clone:1D11) and CoraLite®488-conjugated streptavidin (red) or unstained (blue). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: CMSP humaines,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

Biotin-65643 cible CD314/NKG2D dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Mouse / IgG2a
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Lignée cellulaire NKL
• Nom complet: killer cell lectin-like receptor subfamily K, member 1
• Masse moléculaire calculée: 25 kDa
• Numéro d’acquisition GenBank: BC039836
• Symbole du gène: KLRK1
• Identification du gène (NCBI): 22914
• Conjugaison: Biotin
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Avoid exposure to light. Stable for one year after shipment.

Informations générales

CD314, also known as NKG2D or Killer cell lectin-like receptor subfamily K member 1 (KLRK1), is a type II lectin-like transmembrane stimulatory receptor (PMID: 8436421). In humans, it is expressed on NK cells, gamma delta T cells, and CD8+ alpha beta T cells (PMID: 10426993). Various families of cell surface ligands have been identified, including the MICA/MICB and ULBP proteins (PMID: 12150888). CD314 is involved in both innate and adaptive immunities, and the NKG2D/NKG2DL pathway involves multiple effector cell types for controlling tumor progression (PMID: 31720075).

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