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Anticorps Polyclonal de lapin anti-CD32A/C

CD32A/C Polyclonal Antibody for WB, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

WB, Indirect ELISA

Conjugaison

Non conjugué

N° de cat : 25323-1-PBS

Synonymes

Galerie de données de validation

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  • Western Blot (WB) analysis of various lysates using CD32A/C Polyclonal antibody (25323-1-AP)

    WB analysis using 25323-1-AP (same clone as 25323-1-PBS)

    Various lysates were subjected to SDS PAGE followed by western blot with 25323-1-AP (CD32A/C antibody) at dilution of 1:3000 incubated at room temperature for 1.5 hours. This data was developed using the same antibody clone with 25323-1-PBS in a different storage buffer formulation.

Informations sur le produit

25323-1-PBS cible CD32A/C dans les applications de WB, Indirect ELISA et montre une réactivité avec des échantillons Humain

Réactivité Humain
Hôte / Isotype Lapin / IgG
Clonalité Polyclonal
Type Anticorps
Immunogène CD32A/C Protéine recombinante Ag18123
Nom complet Fc fragment of IgG, low affinity IIc, receptor for (CD32)
Masse moléculaire calculée 323 aa, 36 kDa
Poids moléculaire observé40 kDa
Numéro d’acquisition GenBankBC137397
Symbole du gène CD32A/C
Identification du gène (NCBI) 9103
Conjugaison Non conjugué
Forme Liquide
Méthode de purification Purification par affinité contre l'antigène
Tampon de stockage PBS only
Conditions de stockageStore at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

IgG Fc receptors (FcγRs) play important roles in immune responses. The low-affinity IgG Fc receptor, FcγRII (CD32), consists of a family of primarily cell membrane receptor proteins: CD32A, CD32B, and CD32C. They are encoded by the mRNA splice variants of three highly related genes: FCGR2A, FCGR2B, and FCGR2C (PMID: 30941127). CD32 is present on phagocytic cells such as macrophages and neutrophils, and is involved in the process of phagocytosis and clearing of immune complexes. This antibody raised against 254-323 aa of human CD32C (FCGR2C) can recognize both CD32A and CD32C forms.

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