Anticorps Recombinant de lapin anti-CD336

CD336 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

CloneNo.

242228B9

N° de cat : 98371-1-PBS

Synonymes

NCR2, LY95, Lymphocyte antigen 95 homolog, Natural killer cell p44-related protein, NK cell activating receptor

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Galerie de données de validation

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  FC experiment of Transfected HEK-293T using 98371-1-RR (same clone as 98371-1-PBS)

  1x10^6 HEK-293T cells or CD336 Transfected HEK-293T cells were stained with 0.25 ug Anti-Human CD336 Rabbit RecAb (98371-1-RR, Clone:242228B9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98371-1-PBS in a different storage buffer formulation.

• 

  FC experiment of Transfected HEK-293T using 98371-1-RR (same clone as 98371-1-PBS)

  1x10^6 HEK-293T cells or CD336 Transfected HEK-293T cells were stained with 0.25 ug Anti-Human CD336 Rabbit RecAb (98371-1-RR, Clone:242228B9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L)(red), or Rabbit IgG Isotype Control RecAb (98136-1-RR, Clone: 240953C9) (blue). Cells were fixed with 4% PFA and permeabilized with Flow Cytometry Perm Buffer (PF00011-C). This data was developed using the same antibody clone with 98371-1-PBS in a different storage buffer formulation.

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Informations sur le produit

98371-1-PBS cible CD336 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: natural cytotoxicity triggering receptor 2
• Masse moléculaire calculée: 31 kDa
• Numéro d’acquisition GenBank: NM_004828
• Symbole du gène: CD336
• Identification du gène (NCBI): 9436
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD336, also named as NCR2, LY95 and NKp44, belongs to the natural cytotoxicity receptor (NCR) family. It is cytotoxicity-activating receptor that may contribute to the increased efficiency of activated natural killer (NK) cells to mediate tumor cell lysis. It is expressed on activated human NK cells. CD336 displays a single extracellular Ig-like V domain and a transmembrane portion containing the charged residue (Lysine), likely involved in the association with KARAP/DAP12 molecules. The antibody is specific to CD336.

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