Anticorps Recombinant de lapin anti-CD34

CD34 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240659B11

N° de cat : 98069-1-PBS

Synonymes

CD34 antigen, 240659B11

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Galerie de données de validation

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  FC experiment of C57BL/6 mouse bone marrow cells using 98069-1-RR (same clone as 98069-1-PBS)

  1x10^6 C57BL/6 mouse bone marrow cells were surface stained with 0.25 ug Anti-Mouse CD34 Rabbit Recombinant Antibody (98069-1-RR, Clone:240659B11) and PE-Conjugated AffiniPure Goat Anti-Rabbit IgG(H+L), or 0.25 ug Isotype Control . Cells were not fixed. This data was developed using the same antibody clone with 98069-1-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 98069-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98069-1-RR against Mouse CD34 were performed. The affinity constant is 3.45 nM.

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Informations sur le produit

98069-1-PBS cible CD34 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: CD34 antigen
• Masse moléculaire calculée: 41 kDa
• Numéro d’acquisition GenBank: NM_133654
• Symbole du gène: CD34
• Identification du gène (NCBI): 12490
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C.

Informations générales

CD34 is a 105- to 120-kDa glycophosphoprotein expressed on the majority of hematopoietic stem/progenitor cells, bone marrow stromal cells, capillary endothelial cells, embryonic fibroblasts, and some nerve tissue. CD34 is a commonly used marker for identifying human hematopoietic stem/progenitor cells and mediates cell adhesion and lymphocyte homing by binding L-selectin and E-selectin ligands. CD34 is also one of the best negative selection markers for characterizing and/or isolating human MSCs from bone marrow and other sources. Along with other positive selection markers (such as CD29, CD44, CD90, CD105 and CD166), negative selection markers (such as CD34 and CD45) are used for MSC identification.

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