Anticorps Recombinant de lapin anti-TREM-1/CD354

TREM-1/CD354 Recombinant Antibody for FC

Hôte / Isotype

Lapin / IgG

Réactivité testée

souris

Applications

FC

Conjugaison

Non conjugué

CloneNo.

240219H1

N° de cat : 98022-1-RR

Synonymes

CD354/TREM-1, Trem1, TREM-1, TREM 1, CD354

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Galerie de données de validation

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  FC experiment of mouse splenocytes using 98022-1-RR

  1x10^6 mouse splenocytes were surface stained with 0.25 ug Anti-Mouse TREM-1/CD354 Rabbit Recombinant Antibody (98022-1-RR, Clone:240219H1) or Rabbit IgG Isotype Control Recombinant Antibody (98136-1-RR, Clone: 240953C9) and PE-Conjugated Goat Anti-Rabbit IgG(H+L). Cells were then stained with APC Anti-Mouse Ly-6G/Ly-6C (Gr-1) (RB6-8C5) (APC-65140, Clone: RB6-8C5). Cells were not fixed.

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  Affinity and Kinetic Characterization of 98022-1-RR

  Biolayer interferometry (BLl) kinetic assays of 98022-1-RR against Mouse CD354/TREM-1 were performed. The affinity constant is 91.8 nM.

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Applications testées

• Résultats positifs en cytométrie: splénocytes de souris,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Informations sur le produit

98022-1-RR cible TREM-1/CD354 dans les applications de FC et montre une réactivité avec des échantillons souris

• Réactivité: souris
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: Protéine recombinante
• Nom complet: triggering receptor expressed on myeloid cells 1
• Masse moléculaire calculée: 25 kDa
• Numéro d’acquisition GenBank: NM_021406.5
• Symbole du gène: Trem1
• Identification du gène (NCBI): 58217
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Protein A purfication
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Stable for one year after shipment.

Informations générales

Triggering receptor expressed on myeloid cells 1 (TREM-1, also known as CD354) is a member of the immunoglobulin superfamily, which is expressed on neutrophils and monocytes. TREM1 plays a role in the innate immune system. TREM1 amplifies neutrophil and monocyte-mediated inflammatory responses triggered by bacterial and fungal infections by stimulating release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers.

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