Anticorps Monoclonal anti-CD36

CD36 Monoclonal Antibody for FC

Hôte / Isotype

Mouse / IgM, kappa

Réactivité testée

Humain

Applications

FC

Conjugaison

Non conjugué

Publications(1)

CloneNo.

SMΦ

N° de cat : 65248-1-Ig

Synonymes

PAS 4, GPIV, GPIIIB, GP4, GP3B

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Galerie de données de validation

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  FC experiment of human peripheral blood platelets using 65248-1-Ig

  100ul human peripheral blood platelets (diluted 1:2 in PBS) were surface stained with 0.2 ug Anti-Human CD36 (65248-1-Ig, Clone:SMΦ) or Mouse IgM Isotype Control (65243-1-Ig) and CoraLite®647-conjugated F(ab')2 Fragment Goat Anti-Mouse IgG (H+L) (SA00014-8). Cells were not fixed.

• 

  FC experiment of human peripheral blood platelets using 65248-1-Ig

  100ul human peripheral blood platelets (diluted 1:2 in PBS) were surface stained with 0.2 ug Anti-Human CD36 (65248-1-Ig, Clone:SMΦ) or Mouse IgM Isotype Control (65243-1-Ig) and CoraLite®647-conjugated F(ab')2 Fragment Goat Anti-Mouse IgG (H+L) (SA00014-8). Cells were not fixed.

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Applications testées

• Résultats positifs en cytométrie: plaquettes de sang périphérique humain,

Dilution recommandée

Application	Dilution
This reagent has been tested for flow cytometric analysis. It is recommended that this reagent should be titrated in each testing system to obtain optimal results.
Sample-dependent, check data in validation data gallery

Applications publiées

• FC: See 1 publications below

Informations sur le produit

65248-1-Ig cible CD36 dans les applications de FC et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Réactivité citée: Humain
• Hôte / Isotype: Mouse / IgM, kappa
• Clonalité: Monoclonal
• Type: Anticorps
• Immunogène: s/o
• Nom complet: CD36 molecule (thrombospondin receptor)
• Masse moléculaire calculée: 472 aa, 53 kDa
• Numéro d’acquisition GenBank: BC008406
• Symbole du gène: CD36
• Identification du gène (NCBI): 948
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par affinité
• Tampon de stockage: PBS with 0.09% sodium azide
• Conditions de stockage: Store at 2-8°C. Stable for one year after shipment.

Informations générales

CD36, also named as GP3B and GP4, is an 88-kDa membrane glycoprotein present on platelets, monocytes, erythroid precursors, endothelial cells, and several tumor cell lines. CD36 binds to collagen, thrombospondin, anionic phospholipids, long chain fatty acids and may function in the transport and/or as a regulator of fatty acid transport and oxidized LDL. CD36 may function as a cell adhesion molecule. It mediates cytoadherence of Plasmodium falciparum parasitized erythrocytes. Mutation of CD36 will cause platelet glycoprotein IV deficiency which known as CD36 deficiency. Genetic variations in CD36 are associated with susceptibility to coronary heart disease type 7 (CHDS7).

Publications

Species	Application	Title
human	FC	Eur J Pharmacol; Obacunone Potentiated PD-1 Immunotherapy in Pancreatic Cancer by Mediating CD36; Authors - Chun-Yan Sang

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