Anticorps Recombinant de lapin anti-CD38

CD38 Recombinant Antibody for IHC, Cytometric bead array, Indirect ELISA

Hôte / Isotype

Lapin / IgG

Réactivité testée

Humain

Applications

IHC, Cytometric bead array, Indirect ELISA

Conjugaison

Non conjugué

CloneNo.

241246E3

N° de cat : 84070-3-PBS

Synonymes

241246E3, 2'-phospho-ADP-ribosyl cyclase, 2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase, 2'-phospho-cyclic-ADP-ribose transferase, ADP ribosyl cyclase 1

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Galerie de données de validation

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  IHC staining of human tonsillitis using 84070-3-RR (same clone as 84070-3-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84070-3-RR (CD38 antibody) at dilution of 1:1000 (under 10x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84070-3-PBS in a different storage buffer formulation.

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  IHC staining of human tonsillitis using 84070-3-RR (same clone as 84070-3-PBS)

  Immunohistochemical analysis of paraffin-embedded human tonsillitis tissue slide using 84070-3-RR (CD38 antibody) at dilution of 1:1000 (under 40x lens). Heat mediated antigen retrieval with Tris-EDTA buffer (pH 9.0). This data was developed using the same antibody clone with 84070-3-PBS in a different storage buffer formulation.

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  Affinity and Kinetic Characterization of 84070-3-RR

  Biolayer interferometry (BLl) kinetic assays of 84070-3-RR against Human CD38 were performed. The affinity constant is 1.09 nM.

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Informations sur le produit

84070-3-PBS cible CD38 dans les applications de IHC, Cytometric bead array, Indirect ELISA et montre une réactivité avec des échantillons Humain

• Réactivité: Humain
• Hôte / Isotype: Lapin / IgG
• Clonalité: Recombinant
• Type: Anticorps
• Immunogène: CD38 Protéine recombinante Eg0110
• Nom complet: CD38 molecule
• Masse moléculaire calculée: 300 aa, 34 kDa
• Numéro d’acquisition GenBank: BC007964
• Symbole du gène: CD38
• Identification du gène (NCBI): 952
• Conjugaison: Non conjugué
• Forme: Liquide
• Méthode de purification: Purification par protéine A
• Tampon de stockage: PBS only
• Conditions de stockage: Store at -80°C. 20ul contiennent 0,1% de BSA.

Informations générales

CD38, also known as ADP-ribosyl cyclase 1, is a type II transmembrane glycoprotein with a short N-terminal cytoplasmic tail, a single membrane-spanning domain, and a C-terminal extracellular region with four N-glycosylation sites (PMID: 2319135). The extracellular domain of CD38 has bifunctional enzyme activities that catalyze synthesis of cyclic ADP ribose from nicotinamide adenine dinucleotide (NAD) and hydrolysis of cyclic ADP ribose to adenosine diphosphoribose (PMID: 10636863). CD38 is expressed on a variety of hematopoietic and non-hematopoietic cells and is involved in diverse processes such as generation of calcium-mobilizing metabolites, cell activation, and chemotaxis (PMID: 25938500).

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